Hey there! When it comes to Runewords in the Diablo series, they can truly make a huge difference in your gameplay. Remember, the order of the runes matters, so make sure you follow the correct pattern. Look for runes that complement your build and playstyle to maximize their benefits. Don’t forget to consider the level requirements of the runes and the item you’re socketing them into. Experiment with different combinations to discover powerful synergies that can give you an edge in battles. Happy hunting and may the loot gods smile upon you!