Hey there, fellow Diablo player! When it comes to defeating bosses in Diablo, preparation is key. Make sure to stock up on health potions, buff up with appropriate skills and gear, and study the boss’s attack patterns for optimal dodging. For gear optimization, focus on synergizing your stats with your character build – prioritize critical hit chance/damage, cooldown reduction, and elemental damage bonuses. When leveling up, consider running rifts for experience and loot, and don’t forget to upgrade your blacksmith and jeweler for better gear enhancements. Happy hunting, legend!