Hey there! Enchantments in Diablo can really give you that extra edge in battle. When it comes to optimizing gear with enchantments, focus on enhancing your primary stats like Strength, Dexterity, Intelligence, or Vitality, depending on your character’s build.

For boss fights, consider enchanting your gear with resistances specific to the boss’s elemental attacks to reduce incoming damage. Additionally, look for enchantments that boost your critical hit chance or damage to increase your overall DPS during the fight.

When leveling up, prioritize enchanting gear that gives bonuses to experience gained or reduces resource costs for your abilities. This will help you level up faster and be more efficient in combat.

Remember, experimentation is key in finding the right enchantments for your playstyle and build. Good luck out there in Sanctuary!