Hey fellow Nephalem! When facing bosses in Diablo III, it’s crucial to focus on your build and adapt it to the boss’s mechanics. Make sure to have a good balance between offense and defense. Utilize crowd control skills to manage mobs while focusing on the boss. As for gear optimization, prioritize critical hit chance, critical hit damage, and elemental damage bonuses that match your skills. Don’t forget to upgrade your gems and reroll stats at the Mystic. For efficient leveling, consider running Nephalem Rifts or Greater Rifts at a difficulty where you can quickly clear mobs. Also, keep an eye out for gear upgrades and don’t hesitate to adjust your build as you progress. Good luck in Sanctuary!