Enchantments are crucial in Diablo for boosting your gear’s power. Make sure to prioritize enchanting your main stats such as Strength, Dexterity, Intelligence, or Vitality based on your character’s build. For boss fights, focus on enchanting for increased damage or survivability, depending on the encounter. Additionally, consider enchanting for specific elemental resistances if you’re facing bosses with strong elemental attacks. Remember to farm for high-quality enchanting materials to maximize the benefits of your gear enchantments. Good luck out there, Nephalem!